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MFA Suite™: ETA Application License

$0.00

The MFA Suite™ ETA (Extracellular Timecourse Analysis) application is provided as MATLAB P-code free of charge to licensees.  Once you have completed checkout with this item, you will receive an e-mail with download instructions.

MFA Suite™: INCA Application Academic License

$0.00

MFA Suite™: INCA (ISOTOPOMER NETWORK COMPARTMENTAL ANALYSIS) is a MATLAB-based software package for isotopomer network modeling and metabolic flux analysis. The software can simulate both steady-state and transient isotope labeling experiments using the elementary metabolite unit (EMU) method. It can also estimate pathway fluxes based on extracellular flux measurements, pool size measurements, and/or mass isotopomer measurements supplied to the program. The software can perform a variety of statistical tests to determine goodness-of-fit, to compute parameter confidence intervals (i.e., uncertainty), and to assess model identifiability. It can also perform constraint-based analysis of metabolic networks (e.g., flux balance analysis, flux coupling analysis, etc.) and optimize the design of isotope labeling experiments using computational search algorithms.

The software provides a framework for comprehensive analysis of metabolic networks using mass balances and isotopomer balances. The generation of balance equations and their computational solution is completely automated and can be performed on networks of arbitrary complexity. The graphical user interface (GUI) allows the user to input reaction information and experimental data in a simple format, while offering a variety of powerful analysis tools to design and interpret isotope labeling experiments. All INCA data objects can be loaded and manipulated from the MATLAB command line, and the driver routines can be called directly from the command line or invoked within custom MATLAB scripts. INCA also offers built-in parallelization capabilities for running certain functions within a distributed computing environment.

The MFA Suite™ INCA application is provided as MATLAB P-code free of charge to academic users via our academic online licensing process.

MFA Suite™: INCA Application Commercial Non Exclusive End-User License

$9,000.00

MFA Suite™: INCA (ISOTOPOMER NETWORK COMPARTMENTAL ANALYSIS) is a MATLAB-based software package for isotopomer network modeling and metabolic flux analysis. The software can simulate both steady-state and transient isotope labeling experiments using the elementary metabolite unit (EMU) method. It can also estimate pathway fluxes based on extracellular flux measurements, pool size measurements, and/or mass isotopomer measurements supplied to the program. The software can perform a variety of statistical tests to determine goodness-of-fit, to compute parameter confidence intervals (i.e., uncertainty), and to assess model identifiability. It can also perform constraint-based analysis of metabolic networks (e.g., flux balance analysis, flux coupling analysis, etc.) and optimize the design of isotope labeling experiments using computational search algorithms.

IMPORTANT INFORMATION

  • INCA Application is provided as MATLAB P-code
  • INCA users will need to have independent licenses to MATLAB with Statistics and Optimization Toolboxes
  • The license shown below is designed to commence upon Vanderbilt’s delivery of software download instructions to Licensee and terminate one year from the delivery date
  • This license is designed for use by five or fewer designated users who are employees of the licensee. Please contact us if you have questions about the licensing process

    • MFA Suite™: PIRAMID Application Academic License

    $0.00

    MFA Suite™: PIRAMID (Program for Integration and Rapid Analysis of Mass Isotopomer Distributions) is a user-friendly tool that automates the extraction, quantification, and analysis of MS data sets obtained from stable isotope labeling experiments. PIRAMID can be used for many purposes including: i) automatic peak finding and integration of mass isotopomer distributions (MIDs) of multiple target metabolites from a batch of MS data files; ii) quantification and normalization of integrated ion counts of the target metabolites; iii) generation of statistical comparisons and interactive plots to identify significant differences between two or more experimental conditions or sample time points; and iv) exporting of data into .xls format that can be readily imported by spreadsheet programs or other tools.

    The MFA Suite™ PIRAMID application is provided as MATLAB P-code free of charge to academic users via our academic online licensing process.